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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
44.24
Human Site:
Y84
Identified Species:
60.83
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
Y84
R
W
S
N
S
G
M
Y
L
A
S
G
G
D
D
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
Y84
R
W
S
N
S
G
M
Y
L
A
S
G
G
D
D
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
Y204
R
W
S
N
S
G
M
Y
L
A
S
G
G
D
D
Dog
Lupus familis
XP_543550
1017
111618
Y84
R
W
S
N
S
G
M
Y
L
A
S
G
G
D
D
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
Y84
R
W
S
N
S
G
M
Y
L
A
S
G
G
D
D
Rat
Rattus norvegicus
NP_001129232
1015
111665
Y84
R
W
S
N
S
G
M
Y
L
A
S
G
G
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
Y84
R
W
S
N
N
G
V
Y
L
A
S
G
G
D
D
Frog
Xenopus laevis
Q8QFR2
1013
112021
Y84
R
W
S
N
N
G
A
Y
L
A
S
G
G
D
D
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
Y84
R
W
S
N
N
G
L
Y
L
A
S
G
G
D
D
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
Y84
R
W
S
N
N
G
L
Y
L
A
S
G
G
D
D
Fruit Fly
Dros. melanogaster
O17468
1047
113397
G82
C
V
R
W
S
Q
N
G
Q
N
L
A
S
G
S
Honey Bee
Apis mellifera
XP_001122939
838
91355
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
K30
D
C
H
P
S
G
K
K
F
I
T
C
G
Q
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
L59
N
D
S
K
Q
R
L
L
A
T
L
R
D
H
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
N70
N
C
V
R
W
A
K
N
S
R
Y
V
A
S
G
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
Y84
R
F
S
P
N
G
R
Y
L
A
S
G
A
D
D
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
86.6
86.6
86.6
6.6
0
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
93.3
100
100
6.6
0
26.6
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
6.6
N.A.
0
0
66.6
P-Site Similarity:
N.A.
13.3
N.A.
0
0
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
6
6
0
6
65
0
6
12
0
0
% A
% Cys:
6
12
0
0
0
0
0
0
0
0
0
6
0
0
0
% C
% Asp:
6
6
0
0
0
0
0
0
0
0
0
0
6
65
65
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
6
0
0
0
0
0
0
6
0
0
0
0
0
6
% F
% Gly:
0
0
0
0
0
71
0
6
0
0
0
65
65
6
6
% G
% His:
0
0
6
0
0
0
0
0
0
0
0
0
0
6
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% I
% Lys:
0
0
0
6
0
0
12
6
0
0
0
0
0
0
6
% K
% Leu:
0
0
0
0
0
0
18
6
65
0
12
0
0
0
0
% L
% Met:
0
0
0
0
0
0
36
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
59
30
0
6
6
0
6
0
0
0
0
0
% N
% Pro:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
6
6
0
0
6
0
0
0
0
6
0
% Q
% Arg:
65
0
6
6
0
6
6
0
0
6
0
6
0
0
0
% R
% Ser:
0
0
71
0
48
0
0
0
6
0
65
0
6
6
6
% S
% Thr:
0
0
0
0
0
0
0
0
0
6
6
0
0
0
0
% T
% Val:
0
6
6
0
0
0
6
0
0
0
0
6
0
0
0
% V
% Trp:
0
59
0
6
6
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
65
0
0
6
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _